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Laboratory Safety Manual and Chemical Hygiene Plan

LABORATORY SAFETY MANUAL AND CHEMICAL HYGIENE PLAN

TABLE OF CONTENTS 

Chapter 1.0 - Introduction

  • 1.1 Chemical Hygiene Plan Accessibility
  • 1.2 Laboratory Safety Responsibilities
    • 1.2.1 Environmental Health and Safety
    • 1.2.2 Chemical Hygiene Officer
    • 1.2.3 Deans, Directors, and Department Chairpersons
    • 1.2.4 Principal Investigators, Faculty, and Laboratory Supervisors
    • 1.2.5 Laboratory Employees
    • 1.2.6 Building Coordinators
    • 1.2.7 Department Safety Representatives 

Chapter 2.0 - Engineering Controls

2.1 Chemical Fume Hoods

  • 2.1.1 Perchloric Acid Use
  • 2.1.2 Fume Hood Inspection and Testing Program
  • 2.1.3 Installation of New Fume Hoods
  • 2.1.4 Removal of Existing Fume Hoods
  • 2.1.5 Maintenance Procedures For Fume Hoods

 

2.2 Other Capture Devices

 

 

2.3 Glove Boxes

 

 

2.4 Water Protection in Labs

 

 

Chapter 3.0 - Personal Protective Equipment

3.1 Laboratory Responsibilities for Personal Protective Equipment

3.2 Training for Personal Protective Equipment

 

3.3 Eye Protection
  • 3.3.1 Eye Protection Selection

 

 

3.4 Hand Protection
  • 3.4.1 Selecting the Proper Gloves
  • 3.4.2 Double Gloving
  • 3.4.3 Types of Gloves

 

 

3.5 Protective Clothing

 

 

3.6 Respirators
  • 3.6.1 Respiratory Protection Program

 

 

3.7 Hearing Protection

 

 

3.8 Foot Protection
 

 

 

4.1 Standard Operating Procedures

 

 

4.2 Form 10

 

 

4.3 Procedural Controls

 

 

4.4 Housekeeping

 

 

4.5 Personal Hygiene

 

 

4.6 Eating, Drinking, and Applying Cosmetics in the Lab

 

 

4.7 Working Alone

 

 

4.8 Phones in Labs

 

 

4.9 Unattended Operations

 

 

4.10 Access to Laboratories
  • 4.10.1 Visitors and Children in Labs
  • 4.10.2 Volunteers in Labs
  • 4.10.3 Visiting Scientists and Other Similar Users
  • 4.10.4 Pets in Labs

 

 

4.11 Chemical Purchasing

 

 

4.12 Ordering New Equipment

 

 

4.13 Work Orders and Ticket Requests

 

 

4.14 Changes in Lab Occupancy

 

 

4.15 Laboratory Design and Construction

 

 

4.16 Ventilation Rates
  • 4.16.1 Room Air Pressure in Labs

 

 

4.17 Energy Conservation in Laboratories

 

 

4.18 Green Labs

 

 

4.19 Research Area Inspections
  • 4.19.1 Self Inspections
  • 4.19.2 Inspections by Regulatory Agencies

 

 

4.20 Research Area Space Registration Using HASP

 

 

4.21 Laboratory Security
  • 4.21.1 Security Guidelines

 

 

5.1 Cornell Emergency Plan

  • 5.1.1 Unit Emergency Planning
  • 5.1.2 Evacuation Maps

 

5.2 Emergency Evacuation Procedures

5.3 Emergency Procedures

  • 5.3.1 Laboratory Emergency Shutdown Procedures
  • 5.3.2 Medical Emergency Procedures
  • 5.3.3 First Aid Kits
  • 5.3.4 Fire or Explosion Emergency Procedures
  • 5.3.5 Fire Extinguishers
  • 5.3.6 Power Outage Procedures

 

5.4 Chemical Spill Procedures

  • 5.4.1 Incidental Spills
    • 5.4.1.1 Incidental Spill Cleanup Procedures
  • 5.4.2 Spill Absorbent Materials
  • 5.4.3 Spill Kits
  • 5.4.4 Major Spills
    • 5.4.4.1 Major Spill Cleanup Procedures

 

5.5 Emergency Eyewash and Showers

  • 5.5.1 Testing and Inspection of Emergency Eyewash and Showers
  • 5.5.2 Installation for New Emergency Eyewash and Showers
  • 5.5.3 Maintenance Procedures For Emergency Eyewash and Showers
  • 5.5.4 Using Emergency Eyewash and Showers

 

5.6 Injury/Illness Reporting

5.7 Medical Consultations

  • 5.7.1 Information Provided to the Physician
  • 5.7.2 The Physician’s Written Opinion

 

 

6.1 Training Options

6.2 Cornell Learning Management System

6.3 Laboratory Safety Certificate Program

6.4 Research Administration Certification Program

 

Chapter 7.0 - Safe Chemical Use

7.1 Minimize Exposure to Chemicals

7.2 Understanding Chemical Hazards

  • 7.2.1 Chemical Hazard Information

7.3 Material Safety Data Sheets

  • 7.3.1 SDSs and Newly Synthesized Chemicals

7.4 Routes of Chemical Entry

  • 7.4.1 Inhalation
  • 7.4.2 Ingestion
  • 7.4.3 Injection
  • 7.4.4 Eye and Skin Absorption

 

7.5 Chemical Exposure Limits

7.6 Chemical Exposure Monitoring

7.7 Toxicity

  • 7.7.1 Toxic Effects
  • 7.7.2 Evaluating Toxicity Data

 

7.8 Chemical Labeling

  • 7.8.1 Non-Original Containers
  • 7.8.2 Labeling Requirements

 

7.9 Chemical Storage

  • 7.9.1 General Storage Guidelines

 

7.10 Transporting Chemicals

7.11 Chemical Segregation

  • 7.11.1 EH&S Modified DOT Hazard Class System

 

 

8.1 Explosives

8.2 Flammable and Combustible Liquids

  • 8.2.1 Flammable Storage in Refrigerators/Freezers
  • 8.2.2 Flammable Storage Cabinets

 

8.3 Flammable Solids

8.4 Spontaneously Combustible

8.5 Dangerous When Wet

8.6 Oxidizers and Organic Peroxides

8.7 Peroxide Forming Compounds

8.8 Poisons

8.9 Corrosives

  • 8.9.1 Hydrofluoric Acid
  • 8.9.2 Perchloric Acid

 

 

9.1 Establishment of a Designated Area

9.2 Safe Removal of Contaminated Materials and Waste

9.3 Decontamination Procedures

9.4 Guidelines for Working with Particularly Hazardous Substances

9.5 Prior Approval

9.6 Campus Prior Approval

9.7 Select Carcinogens

9.8 Reproductive Toxins

 

9.9 Acute Toxins

 

 Chapter 10.0 - Hazardous Chemical Waste Disposal

10.1 Hazardous Chemical Waste Container Requirements

10.2 Hazardous Waste Pickup Procedures

 

11.1 Regulated Hazardous Materials

11.2 Hazardous Materials Transportation Requirements

 

Chapter 12.0 - Pesticides

12.1 Pesticide Certification

  • 12.1.1 Exemptions from Pesticide Certification
 

13.1 Institutional Biosafety Committee

  • 13.1.1 Recombinant DNA
  • 13.1.2 Infectious and Pathogenic Agents
  • 13.1.3 Select Biological Agents and Toxins
  • 13.1.4 Gene Therapy

 

13.2 Animal Use

13.3 Human Participants

13.4 Shipping Biological Materials

  • 13.4.1 Permits for the Import and Export of Biological Materials

 

13.5 Biological Safety Cabinets

  • 13.5.1 Biological Safety Cabinet Certifications
  • 13.5.2 BSC Work Practices and Procedures
  • 13.5.3 BSC Operational Procedures
  • 13.5.4 Use of Ultraviolet Lights in the BSC
  • 13.5.5 Types of Biological Safety Cabinets

 

13.6 Biohazardous Waste (Regulated Medical Waste)

  • 13.6.1 Hypodermic Syringes and Needles
 

14.1 Where Ionizing Radiation is Used

14.2 Potential Hazards

  • 14.2.1 How to Protect Yourself

14.3 Control of Ionizing Radiation

14.4 Radioactive Waste Disposal

 
 

16.1 Electrical Safety

  • 16.1.1 Common Electrical Hazards and Preventative Steps
  • 16.1.2 Safe Use of Electrophoresis Equipment

16.2 Machine Guarding

  • 16.2.1 Machine Safety Responsibilities
  • 16.2.2 Common Machine Hazards

16.3 Lighting

16.4 Compressed Gases

  • 16.4.1 Handling Compressed Gas Cylinders
  • 16.4.2 Safe Storage of Compressed Gas Cylinders
  • 16.4.3 Operation of Compressed Gas Cylinders
  • 16.4.4 Return of Cylinders
  • 16.4.5 Hazards of Specific Gases

16.5 Battery Charging

16.6 Heat and Heating Devices

  • 16.6.1 Heat Stress

16.7 Cold Traps

16.8 Autoclaves

16.9 Centrifuges

  • 16.9.1 Centrifuge Rotor Care

16.10 Cryogenic Safety

  • 16.10.1 Cryogenic Safety Guidelines
  • 16.10.2 Cryogenic Chemical Specific Information

16.11 Extractions and Distillations

16.12 Glass Under Vacuum

16.13 Glassware Washing

16.14 General Equipment Set Up

  • 16.14.1 Glassware and Plasticware
  • 16.14.2 Preparation of Glass Tubing and Stoppers
  • 16.14.3 Insertion of Glass Tubes or Rods into Stoppers
  • 16.14.4 Assembling Apparatus
  • 16.14.5 Mercury Containing Equipment

16.15 Ergonomics

 

Appendix A: Chemical Hygiene Plan

 

Appendix B: Contact List

 

Appendix C: Compiled PI Lab Safety Responsibilities

 

Appendix D: Standard Operating Procedure Examples

 

Appendix E: Lab Move Guide

 

Appendix F: Glove Selection For Specific Chemicals

 

Appendix G: EH&S Video Library

 

Appendix H: How To Understand MSDSs

 

Appendix I: Hazards Of Functional Groups

 

Appendix J: Peroxide Forming Chemicals

 

Appendix K: Incompatible Chemicals

 

Appendix L: EH&S Segregation Scheme

 

Appendix M: Sample Prior Approval Form

 

Appendix N: Laser Registration Form

 

Appendix O: EH&S Reference Library  

 

Appendix P: Phenol First Aid Guide

 

 
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