Appendix J - Peroxide Chem

Peroxide Forming Chemicals 

  

SAFE STORAGE PERIODS FOR PEROXIDE FORMERS
Unopened chemicals from manufacturer
18 months or (expiration date)
 
 
Opened containers:
 
Chemicals in Table A
3 months
Chemicals in Tables B and D
12 months
Uninhibited chemicals in Table C
24 hours
Inhibited chemicals in Table C
(Do not store under an inert atmosphere)
12 months
  
 
A. Chemicals that form explosive levels of peroxides without concentration
Butadienea
Isopropyl ether
Sodium amide (sodamide)
Chloroprenea
Potassium metal
Tetrafluoroethylenea
Divinylacetylene
Potassium amide
Vinylidene chloride
 
 B. Chemicals that form explosive levels of peroxides on concentration
Acetal
Diethyl ether
4-Methyl-2-pentanol
Acetaldehyde
Diethylene glycol dimethyl
ether (diglyme)
2-Pentanol
Benzyl alcohol
Dioxanes
4-Penten-1-ol
2-Butanol
Ethylene glycol dimethyl
ether (glyme)
1-Phenylethanol
Cumene
4-Heptanol
2-Phenylethanol
2-Cyclohexen-1-ol
2-Hexanol
2-Propanol
Cyclohexene
Methylacetylene
Tetrahydrofuran
Decahydronaphthalene
3-Methyl-1-butanol
Tetrahydronaphthalene
Diacetylene
Methylcyclopentane
Vinyl ethers
Dicyclopentadiene
Methyl isobutyl ketone
Other secondary alcohols
 
C. Chemicals that may autopolymerize as a result of peroxide accumulation
Acrylic acidb
Methyl methacrylateb
Vinyl chloride
Acrylonitrileb
Styrene
Vinylpyridine
Butadienec
Tetrafluoroethylenec
Vinyladiene chloride
Chloroprenec
Vinyl acetate
 
Chlorotrifluoroethylene
Vinylacetylene
 
 
D. Chemicals that may form peroxides but cannot clearly be placed in sections A-C
Acrolein
p-Chlorophenetole
4,5-Hexadien-2-yn-1-ol
Allyl etherd
Cyclooctened
n-Hexyl ether
Allyl ethyl ether
Cyclopropyl methyl ether
o,p-Iodophenetole
Allyl phenyl ether
Diallyl etherd
Isoamyl benzyl etherd
p-(n-Amyloxy)benzoyl
chloride
p-Di-n-butoxybenzene
Isoamyl etherd
n-Amyl ether
1,2-Dibenzyloxyethaned
Isobutyl vinyl ether
Benzyl n-butyl etherd
p-Dibenzyloxybenzened
Isophoroned
Benzyl etherd
1,2-Dichloroethyl ethyl
Ether
B-Isopropoxypropionitriled
Benzyl ethyl etherd
2,4-Dichlorophenetole
Isopropyl 2,4,5-trichloro-
phenoxy- acetate
Benzyl methyl ether
Diethoxymethaned
Limonene
Benzyl 1-napthyl etherd
2,2-Diethoxypropane
1,5-p-Methadiene
1,2-Bis(2-chloroethoxy)
Ethane
Diethyl ethoxymethylene-
Malonate
Methyl p-(n-amyloxy)-
benzoate
Bis(2 ethoxyethyl)ether
Diethyl fumarated
4-Methyl-2-pentanone
Bis(2-(methoxyethoxy)-
ethyl) ether
Diethyl acetald
n-Methylphenetole
Bis(2-chloroethyl)ether
Diethyketenef
2-Methyltetrahydrofuran
Bis(2-ethoxyethyl)adipate
m,o,p-diethoxybenzene
3-Methoxy-1-butyl acetate
Bis(2-ethoxyethyl)phthalate
1,2-Diethoxyethane
2-Methoxyethanol
Bis(2-methoxyethyl)-
Carbonate
Dimethoxymethaned
3-Methoxyethyl acetate
Bis(2-methoxyethyl) ether
1,1-Dimethoxyethaned
2-Methoxyethyl vinyl ether
Bis(2-methoxyethyl)
Phthalate
Dimethylketenef
Methonxy-1,3,5,7-cyclo-
octa-tetraene
Bis(2-methoxymethyl)
Adipate
3,3-Dimethoxypropene
B-Methoxypropionitrile
Bis(2-n-butoxyethyl)
Phthalate
2,4-Dinitrophenetole
m-Nitrophenetole
Bis(2-phenoxyethyl) ether
1,3-Dioxepaned
1-Octene
Bis(4-chlorobutyl) ether
Di(1-propynyl)etherf
Oxybis(2-ethyl acetate)
Bis(chloromethyl) ethere
Di(2-propynyl)ether
Oxybis(2-ethyl benzoate)
2-Bromomethyl ethyl ether
Di-n-propoxymethaned
B,B-oxydipropionitrile
B-Bromophenetole
1,2-Epoxy-3-isopropoxy-
propaned
1-Pentene
o-Bromophenetole
1,2-Epoxy-3-phenoxy-
propane
Phenoxyacetyl chloride
p-Bromophenetole
p-Ethoxyacethophenone
a-Phenoxypropionyl chloride
3-Bromopropyl phenyl ether
2-Ethoxyethyl acetate
Phenyl o-propyl ether
1,3-Butadiyne
(2-Ethoxyethyl)-o-benzoyl
benzoate
p-Phenylphenetone
Buten-3-yne
1-(2-Ethoxyethoxy)ethyl
acetate
n-Propyl ether
tert-Butyl ethyl ether
1-Ethoxynaphthalene
n-Propyl isopropyl ether
tert-Butyl methyl ether
o,p-Ethoxyphenyl
isocyanate
Sodium 8,11,14-eicosa-
tetraenoate
 
n-Butyl phenyl ether
1-Ethoxy-2-propyne
Sodium ethoxyacetylidef
n-Butyl vinyl ether
3-Ethoxyopropionitrile
Tetrahydropyran
Chloroacetaldehyde
diethylacetald
2-Ethylacrylaldehyde oxime
Triethylene glycol diacetate
2-Chlorobutadiene
2-Ethylbutanol
Triethylene glycol diprop-
ionate
1-(2-Chloroethoxy)-2-
phen-oxyethane
Ethyl B-ethoxypropionate
1,3,3-Trimethoxypropened
Chloroethylene
2-Ethylhexanal
1,1,2,3-Tetrachloro-1,3-
butadiene
Chloromethyl methyl ethere
Ethyl vinyl ether
4-Vinyl cyclohexene
B-Chlorophenetole
Furan
Vinylene carbonate
o-Chlorophenetole
2,5-Hexadiyn-1-ol
Vinylidene chlorided
 
NOTES:
a   When stored as a liquid monomer.
b   Although these chemicals form peroxides, no explosions involving these
    monomers have been reported.
c   When stored in liquid form, these chemicals form explosive levels of peroxides
    without concentration. They may also be stored as a gas in gas cylinders.
    When stored as a gas, these chemicals may autopolymerize as a result of
    peroxide accumulation.
d   These chemicals easily form peroxides and should probably be considered
     under Part B.
e   OSHA - regulated carcinogen.
f    Extremely reactive and unstable compound.
 
 
   

References:

Prudent Practices in the Laboratory, National Research Council, 1995.
“Review of Safety Guidelines for Peroxidizable Organic Chemicals,” Chemical Health
and Safety, September/October 1996
.   

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